Beta-Lactamases and ESBL

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Antibiotic impregnated tablets for screening ESBL and AmpC beta lactamases

Antibiotic resistance is a growing threat. Fifty non repetitive multi drug resistant gram negative bacterial isolates were screened for ESBL, AmpC, ESBL-AmpC co-production using antibiotic tablets. Of these 56% were Escherichia coli, 16% were Klebsiella spp., 39.6% produced ESBLs, 17.2% AmpC and 13.8% showed co-production. Antibiotic tablets sensitivity for ESBL detection was 93.9% compared to ...

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Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.

BACKGROUND & OBJECTIVE Production of extended spectrum beta-lactamases (ESBLs) and AmpC beta-lactamases are the most common mechanisms of antimicrobial resistance in Gram negative bacilli. A prospective study was undertaken to know the occurrence of ESBL and AmpC producing strains and their antibiotic susceptibilities to newer agents to guide empirical therapy for complicated urinary tract infe...

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Extended - spectrum Beta - lactamases

Beta-lactamase enzymes (BLs) have become the most worrisome mediators of antimicrobial resistance expressed by gram-negative bacteria (GNB). The multiple families of BLs have in common the ability to hydrolyze the -lactam rings of one or more members of the penicillins, cephalosporins, cephamycins, carbapenems, and monobactams. Extended-spectrum -lactamases (ESBLs) are a subset of BLs that conf...

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Extended-spectrum beta-lactamases.

At least 30 extended-spectrum beta-lactamases (ESB) have emerged responsible for resistance to indigestible beta-lactams (C3G) since their discovery in West Germany in 1983. Most of them are produced by enterobacteria and essentially K. pneumoniae which appeared susceptible to oxyimino-beta-lactams. A double-disk test was useful to detect such nosocomial isolates of enterobacteria (urines, bloo...

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New diagnostic microarray (Check-KPC ESBL) for detection and identification of extended-spectrum beta-lactamases in highly resistant Enterobacteriaceae.

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ژورنال

عنوان ژورنال: Virology & Immunology Journal

سال: 2019

ISSN: 2577-4379

DOI: 10.23880/vij-16000225